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BH3 Mimetics for the Treatment of Prostate Cancer

Despite improved diagnostic and therapeutic intervention, advanced prostate cancer (PC) remains incurable. The acquired resistance of PC cells to current treatment protocols has been traced to apoptosis resistance based on the upregulation of anti-apoptotic proteins of the Bcl-2 family. The use of B...

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Bibliographic Details
Published in:Front Pharmacol
Main Author: Wolf, Philipp
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563364/
https://ncbi.nlm.nih.gov/pubmed/28868037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00557
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