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Directed evolution of specific receptor–ligand pairs for use in the creation of gene switches
Despite their versatility and power in controlling gene regulation in nature, nuclear hormone receptors (NHRs) have largely eluded utility in heterologous gene regulation applications such as gene therapy and metabolic engineering. The main reason for this void is the pleiotropic interference of the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556283/ https://ncbi.nlm.nih.gov/pubmed/15811944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409206102 |
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