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Failure to Deliver and Translate—New Insights into RNA Dysregulation in ALS

Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal neurodegenerative disease affecting both upper and lower motor neurons. The molecular mechanisms underlying disease pathogenesis remain largely unknown. Multiple genetic loci including genes involved in proteostasis and ribostasis have b...

詳細記述

保存先:
書誌詳細
出版年:Front Cell Neurosci
主要な著者: Coyne, Alyssa N., Zaepfel, Benjamin L., Zarnescu, Daniela C.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562674/
https://ncbi.nlm.nih.gov/pubmed/28860970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00243
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