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RNA Is a Double-Edged Sword in ALS Pathogenesis

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease that affects upper and lower motor neurons. Familial ALS accounts for a small subset of cases (<10–15%) and is caused by dominant mutations in one of more than 10 known genes. Multiple genes have been causall...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Zaepfel, Benjamin L., Rothstein, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326408/
https://ncbi.nlm.nih.gov/pubmed/34349625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.708181
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