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Tau hyperphosphorylation induces apoptotic escape and triggers neurodegeneration in Alzheimer’s disease

Since abnormal post-translational modifications or gene mutations of tau have been detected in over twenty neurodegenerative disorders, tau has attracted widespread interest as a target protein. Among its various post-translational modifications, phosphorylation is the most extensively studied. It i...

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Publicat a:Neurosci Bull
Autors principals: Wang, Jian-Zhi, Wang, Zhi-Hao, Tian, Qing
Format: Artigo
Idioma:Inglês
Publicat: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562660/
https://ncbi.nlm.nih.gov/pubmed/24627329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1415-y
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