Ritterostatin G(N)1(N), a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78**

Natural products discovered using agnostic approaches, unlike rationally designed or HTS obtained leads, offer the ability to reveal new biological pathways, and hence, serve as an important vehicle to unveil new avenues in drug discovery. The ritterazine-cephalostatin family of natural products dis...

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Publicado en:Chembiochem
Autores principales: Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kanduluru, Ananda Kumar, Fuchs, Philip L., Cang, Hu, Costa-Lotufo, Letícia V., Chapman, Eli, La Clair, James J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562448/
https://ncbi.nlm.nih.gov/pubmed/28074539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600669
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