Ritterostatin G(N)1(N), a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78**

Natural products discovered using agnostic approaches, unlike rationally designed or HTS obtained leads, offer the ability to reveal new biological pathways, and hence, serve as an important vehicle to unveil new avenues in drug discovery. The ritterazine-cephalostatin family of natural products dis...

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Bibliografiske detaljer
Udgivet i:Chembiochem
Main Authors: Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kanduluru, Ananda Kumar, Fuchs, Philip L., Cang, Hu, Costa-Lotufo, Letícia V., Chapman, Eli, La Clair, James J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562448/
https://ncbi.nlm.nih.gov/pubmed/28074539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600669
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