Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity

Telomere dysfunction has been associated with chromosomal instability in colorectal carcinoma, but the consequences of telomere-dependent instability for chromosome integrity and clonal evolution have been little explored. We show here that abnormally short telomeres lead to a wide spectrum of mitot...

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Detaylı Bibliyografya
Asıl Yazarlar: Stewénius, Ylva, Gorunova, Ludmila, Jonson, Tord, Larsson, Nina, Höglund, Mattias, Mandahl, Nils, Mertens, Fredrik, Mitelman, Felix, Gisselsson, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC556242/
https://ncbi.nlm.nih.gov/pubmed/15809428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408454102
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