WBSCR16 is a Guanine Nucleotide Exchange Factor (GEF) Important for Mitochondrial Fusion

Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2, and by inner membrane GTPase OPA1. Disordered mitochondrial fusi...

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Publicat a:Cell Rep
Autors principals: Huang, Guorui, Massoudi, Dawiyat, Muir, Alison M., Joshi, Dinesh C., Zhang, Chuan-Li, Chiu, Shing Yan, Greenspan, Daniel S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562410/
https://ncbi.nlm.nih.gov/pubmed/28746876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.090
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