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WBSCR16 is a Guanine Nucleotide Exchange Factor (GEF) Important for Mitochondrial Fusion

Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2, and by inner membrane GTPase OPA1. Disordered mitochondrial fusi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Huang, Guorui, Massoudi, Dawiyat, Muir, Alison M., Joshi, Dinesh C., Zhang, Chuan-Li, Chiu, Shing Yan, Greenspan, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562410/
https://ncbi.nlm.nih.gov/pubmed/28746876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.090
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