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Identification of the control region for tissue-specific imprinting of the stimulatory G protein α-subunit

Gnas is a complex gene with multiple imprinted promoters. The upstream Nesp and Nespas/Gnasxl promoters are paternally and maternally methylated, respectively. The downstream promoter for the stimulatory G protein α-subunit (G(s)α) is unmethylated, although in some tissues (e.g., renal proximal tubu...

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Autors principals: Liu, Jie, Chen, Min, Deng, Chuxia, Bourc'his, Déborah, Nealon, Julie G., Erlichman, Beth, Bestor, Timothy H., Weinstein, Lee S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC556240/
https://ncbi.nlm.nih.gov/pubmed/15811946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408262102
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