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A parametric model to estimate the proportion from true null using a distribution for p-values
Microarray studies generate a large number of p-values from many gene expression comparisons. The estimate of the proportion of the p-values sampled from the null hypothesis draws broad interest. The two-component mixture model is often used to estimate this proportion. If the data are generated und...
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Udgivet i: | Comput Stat Data Anal |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2017
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562234/ https://ncbi.nlm.nih.gov/pubmed/28827889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2017.04.008 |
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