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Towards Accurate Estimation of the Proportion of True Null Hypotheses in Multiple Testing

BACKGROUND: Biomedical researchers are now often faced with situations where it is necessary to test a large number of hypotheses simultaneously, eg, in comparative gene expression studies using high-throughput microarray technology. To properly control false positive errors the FDR (false discovery...

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Detalhes bibliográficos
Autor principal: Zhang, Shu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081301/
https://ncbi.nlm.nih.gov/pubmed/21526119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018874
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