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Estimating the proportion of true null hypotheses when the statistics are discrete

Motivation: In high-dimensional testing problems π(0), the proportion of null hypotheses that are true is an important parameter. For discrete test statistics, the P values come from a discrete distribution with finite support and the null distribution may depend on an ancillary statistic such as a...

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Publicat a:Bioinformatics
Autors principals: Dialsingh, Isaac, Austin, Stefanie R., Altman, Naomi S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495288/
https://ncbi.nlm.nih.gov/pubmed/25735771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv104
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