P18 peptide, a functional fragment of pigment epithelial-derived factor, inhibits angiogenesis in hepatocellular carcinoma via modulating VEGF/VEGFR2 signalling pathway

The P18 peptide is a functional fragment of pigment epithelial-derived factor (PEDF), which is an endogenic angiogenesis inhibitor. This study sought to determine the anti-angiogenic bioactivity of the P18 peptide in hepatocellular carcinoma (HCC) and to elucidate the underlying mechanism. Xenograft...

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Veröffentlicht in:Oncol Rep
Hauptverfasser: Wang, Xin, Xiu, Peng, Wang, Fuhai, Zhong, Jingtao, Wei, Honglong, Xu, Zongzhen, Liu, Feng, Li, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562001/
https://ncbi.nlm.nih.gov/pubmed/28627623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5719
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