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Inhibition of VEGF(165)/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis
Hepatocellular carcinoma (HCC) relies on angiogenesis for growth and metastasis. Leukocyte cell-derived chemotaxin 2 (LECT2) is a cytokine and preferentially expressed in the liver. Previous studies have found that LECT2 targets to both immune and tumor cells to suppress HCC development and vascular...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979047/ https://ncbi.nlm.nih.gov/pubmed/27507763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31398 |
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