Natural killer cell–mediated inflammation resolution is disabled in severe asthma

Severe asthma is typically characterized by chronic airway inflammation that is refractory to corticosteroids and associated with excess morbidity. Patients were recruited into the National Heart, Lung, and Blood Institute–sponsored Severe Asthma Research Program and comprehensively phenotyped by br...

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Udgivet i:Sci Immunol
Main Authors: Duvall, Melody G., Barnig, Cindy, Cernadas, Manuela, Ricklefs, Isabell, Krishnamoorthy, Nandini, Grossman, Nicole L., Bhakta, Nirav R., Fahy, John V., Bleecker, Eugene R., Castro, Mario, Erzurum, Serpil C., Gaston, Benjamin M., Jarjour, Nizar N., Mauger, David T., Wenzel, Sally E., Comhair, Suzy A., Coverstone, Andrea M., Fajt, Merritt L., Hastie, Annette T., Johansson, Mats W., Peters, Michael C., Phillips, Brenda R., Israel, Elliot, Levy, Bruce D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561743/
https://ncbi.nlm.nih.gov/pubmed/28783702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aam5446
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