Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance

Peroxisome proliferator-activated receptor γ (PPARγ) plays a crucial role in adipocyte differentiation, glucose metabolism, and other physiological processes. To further explore the role of PPARγ in adipose tissues, we used a Cre/loxP strategy to generate adipose-specific PPARγ knockout mice. These...

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Autors principals: Jones, Julie R., Barrick, Cordelia, Kim, Kyoung-Ah, Lindner, Jill, Blondeau, Bertrand, Fujimoto, Yuka, Shiota, Masakazu, Kesterson, Robert A., Kahn, Barbara B., Magnuson, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC556131/
https://ncbi.nlm.nih.gov/pubmed/15833818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306743102
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