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Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin
Linker histone H1 is an important structural component of chromatin that stabilizes the nucleosome and compacts the nucleofilament into higher-order structures. The biology of histone H1 remains, however, poorly understood. Here we show that Drosophila histone H1 (dH1) prevents genome instability as...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561251/ https://ncbi.nlm.nih.gov/pubmed/28819201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00338-5 |
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