Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease

PGC-1α is a versatile inducer of mitochondrial biogenesis and responsive to the changing energy demands of the cell. As mitochondrial ATP production requires proteins that derive from translation products of cytosolic ribosomes, we asked whether PGC-1α directly takes part in ribosomal biogenesis. He...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Jesse, Sarah, Bayer, Hanna, Alupei, Marius C., Zügel, Martina, Mulaw, Medhanie, Tuorto, Francesca, Malmsheimer, Silke, Singh, Karmveer, Steinacker, Jürgen, Schumann, Uwe, Ludolph, Albert C., Scharffetter-Kochanek, Karin, Witting, Anke, Weydt, Patrick, Iben, Sebastian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561056/
https://ncbi.nlm.nih.gov/pubmed/28819135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09148-7
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