Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation

Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Meley, Daniel, Héraud, Audrey, Gouilleux-Gruart, Valerie, Ivanes, Fabrice, Velge-Roussel, Florence
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561017/
https://ncbi.nlm.nih.gov/pubmed/28861079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00926
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