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Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation

Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Meley, Daniel, Héraud, Audrey, Gouilleux-Gruart, Valerie, Ivanes, Fabrice, Velge-Roussel, Florence
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561017/
https://ncbi.nlm.nih.gov/pubmed/28861079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00926
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