Unexpected impairment of TNF-α-induced maturation of human dendritic cells in vitro by IL-4

BACKGROUND: An efficient strategy for programing dendritic cells (DCs) for cancer immunotherapy is the optimization of their maturation so that they can efficiently stimulate cancer-specific T cell responses. Interleukin (IL)-4 has appeared as an essential cytokine, widely used in vitro with granulo...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Chabot, Valérie, Martin, Laurence, Meley, Daniel, Sensebé, Luc, Baron, Christophe, Lebranchu, Yvon, Dehaut, Frédéric, Velge-Roussel, Florence
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832484/
https://ncbi.nlm.nih.gov/pubmed/27080531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0848-2
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