The Orai-1 and STIM-1 Complex Controls Human Dendritic Cell Maturation

Ca(2+) signaling plays an important role in the function of dendritic cells (DC), the professional antigen presenting cells. Here, we described the role of Calcium released activated (CRAC) channels in the maturation and cytokine secretion of human DC. Recent works identified STIM1 and Orai1 in huma...

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Bibliographic Details
Main Authors: Félix, Romain, Crottès, David, Delalande, Anthony, Fauconnier, Jérémy, Lebranchu, Yvon, Le Guennec, Jean-Yves, Velge-Roussel, Florence
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659124/
https://ncbi.nlm.nih.gov/pubmed/23700407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061595
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