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cAMP-dependent regulation of I(Ks) single-channel kinetics
The delayed potassium rectifier current, I(Ks), is composed of KCNQ1 and KCNE1 subunits and plays an important role in cardiac action potential repolarization. During β-adrenergic stimulation, 3′-5′-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) phosphorylates KCNQ1, producin...
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| Pubblicato in: | J Gen Physiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560775/ https://ncbi.nlm.nih.gov/pubmed/28687606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611734 |
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