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A parapoxviral virion protein inhibits NF-κB signaling early in infection

Poxviruses have evolved unique proteins and mechanisms to counteract the nuclear factor κB (NF-κB) signaling pathway, which is an essential regulatory pathway of host innate immune responses. Here, we describe a NF-κB inhibitory virion protein of orf virus (ORFV), ORFV073, which functions very early...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Khatiwada, Sushil, Delhon, Gustavo, Nagendraprabhu, Ponnuraj, Chaulagain, Sabal, Luo, Shuhong, Diel, Diego G., Flores, Eduardo F., Rock, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560748/
https://ncbi.nlm.nih.gov/pubmed/28787456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006561
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