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A parapoxviral virion protein targets the retinoblastoma protein to inhibit NF-κB signaling
Poxviruses have evolved multiple strategies to subvert signaling by Nuclear Factor κB (NF-κB), a crucial regulator of host innate immune responses. Here, we describe an orf virus (ORFV) virion-associated protein, ORFV119, which inhibits NF-κB signaling very early in infection (≤ 30 min post infectio...
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| Vydáno v: | PLoS Pathog |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5747488/ https://ncbi.nlm.nih.gov/pubmed/29244863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006779 |
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