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Orf Virus ORFV121 Encodes a Novel Inhibitor of NF-κB That Contributes to Virus Virulence

Orf virus (ORFV), the type member of the genus Parapoxvirus of the Poxviridae, has evolved novel strategies (proteins and/or mechanisms of action) to modulate host cell responses regulated by the nuclear factor-κB (NF-κB) signaling pathway. Here, we present data indicating that ORFV ORFV121, a gene...

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Autors principals: Diel, D. G., Luo, S., Delhon, G., Peng, Y., Flores, E. F., Rock, D. L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067802/
https://ncbi.nlm.nih.gov/pubmed/21177808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02236-10
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