The ORF61 Protein Encoded by Simian Varicella Virus and Varicella-Zoster Virus Inhibits NF-κB Signaling by Interfering with IκBα Degradation

Varicella-zoster virus (VZV) causes chickenpox upon primary infection and establishes latency in ganglia. Reactivation from latency causes herpes zoster, which may be complicated by postherpetic neuralgia. Innate immunity mediated by interferon and proinflammatory cytokines represents the first line...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Whitmer, Travis, Malouli, Daniel, Uebelhoer, Luke S., DeFilippis, Victor R., Früh, Klaus, Verweij, Marieke C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524061/
https://ncbi.nlm.nih.gov/pubmed/26085158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01149-15
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