The ORF61 Protein Encoded by Simian Varicella Virus and Varicella-Zoster Virus Inhibits NF-κB Signaling by Interfering with IκBα Degradation

Varicella-zoster virus (VZV) causes chickenpox upon primary infection and establishes latency in ganglia. Reactivation from latency causes herpes zoster, which may be complicated by postherpetic neuralgia. Innate immunity mediated by interferon and proinflammatory cytokines represents the first line...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Whitmer, Travis, Malouli, Daniel, Uebelhoer, Luke S., DeFilippis, Victor R., Früh, Klaus, Verweij, Marieke C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524061/
https://ncbi.nlm.nih.gov/pubmed/26085158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01149-15
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