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Human tissue models in cancer research: looking beyond the mouse

Mouse models, including patient-derived xenograft mice, are widely used to address questions in cancer research. However, there are documented flaws in these models that can result in the misrepresentation of human tumour biology and limit the suitability of the model for translational research. A c...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Jackson, Samuel J., Thomas, Gareth J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560067/
https://ncbi.nlm.nih.gov/pubmed/28768734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031260
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