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Human tissue models in cancer research: looking beyond the mouse

Mouse models, including patient-derived xenograft mice, are widely used to address questions in cancer research. However, there are documented flaws in these models that can result in the misrepresentation of human tumour biology and limit the suitability of the model for translational research. A c...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Jackson, Samuel J., Thomas, Gareth J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560067/
https://ncbi.nlm.nih.gov/pubmed/28768734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031260
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