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Human tissue models in cancer research: looking beyond the mouse

Mouse models, including patient-derived xenograft mice, are widely used to address questions in cancer research. However, there are documented flaws in these models that can result in the misrepresentation of human tumour biology and limit the suitability of the model for translational research. A c...

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Detaylı Bibliyografya
Yayımlandı:Dis Model Mech
Asıl Yazarlar: Jackson, Samuel J., Thomas, Gareth J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560067/
https://ncbi.nlm.nih.gov/pubmed/28768734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031260
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