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A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen
A genome-wide ethyl-N-nitrosourea (ENU) mutagenesis screen in mice was performed to identify novel regulators of erythropoiesis. Here, we describe a mouse line, RBC16, which harbours a dominantly inherited mutation in the Cpox gene, responsible for production of the haem biosynthesis enzyme, copropo...
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| Publicado no: | Dis Model Mech |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560062/ https://ncbi.nlm.nih.gov/pubmed/28600349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029116 |
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