An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

BACKGROUND: We have used a sensitized ENU mutagenesis screen to produce mouse lines that carry mutations in genes required for epigenetic regulation. We call these lines Modifiers of murine metastable epialleles (Mommes). RESULTS: We report a basic molecular and phenotypic characterization for twent...

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Hlavní autoři: Daxinger, Lucia, Harten, Sarah K, Oey, Harald, Epp, Trevor, Isbel, Luke, Huang, Edward, Whitelaw, Nadia, Apedaile, Anwyn, Sorolla, Anabel, Yong, Joan, Bharti, Vandhana, Sutton, Joanne, Ashe, Alyson, Pang, Zhenyi, Wallace, Nathan, Gerhardt, Daniel J, Blewitt, Marnie E, Jeddeloh, Jeffrey A, Whitelaw, Emma
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053835/
https://ncbi.nlm.nih.gov/pubmed/24025402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-9-r96
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