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The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

BACKGROUND: We recently identified a novel protein, Rearranged L-myc fusion (Rlf), that is required for DNA hypomethylation and transcriptional activity at two specific regions of the genome known to be sensitive to epigenetic gene silencing. To identify other loci affected by the absence of Rlf, we...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Harten, Sarah K, Oey, Harald, Bourke, Lauren M, Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M, Whitelaw, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381397/
https://ncbi.nlm.nih.gov/pubmed/25857663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0128-2
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