The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

BACKGROUND: We recently identified a novel protein, Rearranged L-myc fusion (Rlf), that is required for DNA hypomethylation and transcriptional activity at two specific regions of the genome known to be sensitive to epigenetic gene silencing. To identify other loci affected by the absence of Rlf, we...

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Pubblicato in:BMC Biol
Autori principali: Harten, Sarah K, Oey, Harald, Bourke, Lauren M, Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M, Whitelaw, Emma
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381397/
https://ncbi.nlm.nih.gov/pubmed/25857663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0128-2
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