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The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

BACKGROUND: We recently identified a novel protein, Rearranged L-myc fusion (Rlf), that is required for DNA hypomethylation and transcriptional activity at two specific regions of the genome known to be sensitive to epigenetic gene silencing. To identify other loci affected by the absence of Rlf, we...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Biol
Κύριοι συγγραφείς: Harten, Sarah K, Oey, Harald, Bourke, Lauren M, Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M, Whitelaw, Emma
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381397/
https://ncbi.nlm.nih.gov/pubmed/25857663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0128-2
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