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Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis
Insulin signaling regulates many facets of animal physiology. Its dysregulation causes diabetes and other metabolic disorders. The spindle checkpoint proteins MAD2 and BUBR1 prevent precocious chromosome segregation and suppress aneuploidy. The MAD2 inhibitory protein p31(comet) promotes checkpoint...
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| Foilsithe in: | Cell |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560052/ https://ncbi.nlm.nih.gov/pubmed/27374329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.074 |
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