The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk

During vertebrate eye morphogenesis, a transient fissure forms at its inferior part, known as the optic fissure. This will gradually close, giving rise to a healthy, spherical optic cup. Failure of the optic fissure to close gives rise to an ocular disorder known as coloboma. During this development...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Smith, Rowena, Huang, Yu-Ting, Tian, Tian, Vojtasova, Dominika, Mesalles-Naranjo, Oscar, Pollard, Steven M., Pratt, Thomas, Price, David J., Fotaki, Vassiliki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559767/
https://ncbi.nlm.nih.gov/pubmed/28729440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0286-17.2017
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