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Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis

Establishment of precise three-dimensional tissue structure is vital for organ function. In the visual system, optic fissure and stalk morphogenesis is a crucial yet poorly understood process, disruptions of which can lead to coloboma, a birth defect causing visual impairment. Here, we use four-dime...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Gordon, Hannah B., Lusk, Sarah, Carney, Keith R., Wirick, Emily O., Murray, Brooke Froelich, Kwan, Kristen M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262791/
https://ncbi.nlm.nih.gov/pubmed/30333214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.165068
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