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In silico investigation of a KCNQ1 mutation associated with short QT syndrome

Short QT syndrome (SQTS) is a rare condition characterized by abnormally ‘short’ QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death. This simulation study investigated arrhythmia dynamics in multi-scale human ventricle models associated with the SQT2-related...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Adeniran, Ismail, Whittaker, Dominic G., El Harchi, Aziza, Hancox, Jules C., Zhang, Henggui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559555/
https://ncbi.nlm.nih.gov/pubmed/28814790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08367-2
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