The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein G(olf) to Olfactory Cilia

BEACH domain proteins are involved in membrane protein traffic and human diseases, but their molecular mechanisms are not understood. The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutations cause severe immune deficiency. Here, we report a first...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kurtenbach, Stefan, Gießl, Andreas, Strömberg, Siv, Kremers, Jan, Atorf, Jenny, Rasche, Sebastian, Neuhaus, Eva M., Hervé, Denis, Brandstätter, Johann Helmut, Asan, Esther, Hatt, Hanns, Kilimann, Manfred W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559528/
https://ncbi.nlm.nih.gov/pubmed/28814779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08543-4
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