The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein G(olf) to Olfactory Cilia

BEACH domain proteins are involved in membrane protein traffic and human diseases, but their molecular mechanisms are not understood. The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutations cause severe immune deficiency. Here, we report a first...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurtenbach, Stefan, Gießl, Andreas, Strömberg, Siv, Kremers, Jan, Atorf, Jenny, Rasche, Sebastian, Neuhaus, Eva M., Hervé, Denis, Brandstätter, Johann Helmut, Asan, Esther, Hatt, Hanns, Kilimann, Manfred W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559528/
https://ncbi.nlm.nih.gov/pubmed/28814779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08543-4
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