Antibacterial photosensitization through activation of coproporphyrinogen oxidase

Gram-positive bacteria cause the majority of skin and soft tissue infections (SSTIs), resulting in the most common reason for clinic visits in the United States. Recently, it was discovered that Gram-positive pathogens use a unique heme biosynthesis pathway, which implicates this pathway as a target...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Surdel, Matthew C., Horvath, Dennis J., Lojek, Lisa J., Fullen, Audra R., Simpson, Jocelyn, Dutter, Brendan F., Salleng, Kenneth J., Ford, Jeremy B., Jenkins, J. Logan, Nagarajan, Raju, Teixeira, Pedro L., Albertolle, Matthew, Georgiev, Ivelin S., Jansen, E. Duco, Sulikowski, Gary A., Lacy, D. Borden, Dailey, Harry A., Skaar, Eric P.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559000/
https://ncbi.nlm.nih.gov/pubmed/28739897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700469114
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