Antibacterial photosensitization through activation of coproporphyrinogen oxidase

Gram-positive bacteria cause the majority of skin and soft tissue infections (SSTIs), resulting in the most common reason for clinic visits in the United States. Recently, it was discovered that Gram-positive pathogens use a unique heme biosynthesis pathway, which implicates this pathway as a target...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Surdel, Matthew C., Horvath, Dennis J., Lojek, Lisa J., Fullen, Audra R., Simpson, Jocelyn, Dutter, Brendan F., Salleng, Kenneth J., Ford, Jeremy B., Jenkins, J. Logan, Nagarajan, Raju, Teixeira, Pedro L., Albertolle, Matthew, Georgiev, Ivelin S., Jansen, E. Duco, Sulikowski, Gary A., Lacy, D. Borden, Dailey, Harry A., Skaar, Eric P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559000/
https://ncbi.nlm.nih.gov/pubmed/28739897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700469114
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