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Mechanism and catalytic strategy of the prokaryotic specific GTP cyclohydrolase IB

GTP cyclohydrolase I catalyzes the first step in folic acid biosynthesis in bacteria and plants, biopterin biosynthesis in mammals, and the biosynthesis of 7-deazaguanosine modified tRNA nucleosides in bacteria and archaea. The type IB GTP cyclohydrolase (GCYH-IB) is a prokaryotic-specific enzyme fo...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Paranagama, Naduni, Bonnett, Shilah A., Alvarez, Jonathan, Luthra, Amit, Stec, Boguslaw, Gustafson, Andrew, Iwata-Reuyl, Dirk, Swairjo, Manal A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558430/
https://ncbi.nlm.nih.gov/pubmed/28126741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20161025
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