Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes

In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce extracellular matrix-supported intestinal tubules in perfused microfluidic devices, exhibiting tissue polarization and transporter expression. Fo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Trietsch, Sebastiaan J., Naumovska, Elena, Kurek, Dorota, Setyawati, Meily C., Vormann, Marianne K., Wilschut, Karlijn J., Lanz, Henriëtte L., Nicolas, Arnaud, Ng, Chee Ping, Joore, Jos, Kustermann, Stefan, Roth, Adrian, Hankemeier, Thomas, Moisan, Annie, Vulto, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557798/
https://ncbi.nlm.nih.gov/pubmed/28811479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00259-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados