Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes

In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce extracellular matrix-supported intestinal tubules in perfused microfluidic devices, exhibiting tissue polarization and transporter expression. Fo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Trietsch, Sebastiaan J., Naumovska, Elena, Kurek, Dorota, Setyawati, Meily C., Vormann, Marianne K., Wilschut, Karlijn J., Lanz, Henriëtte L., Nicolas, Arnaud, Ng, Chee Ping, Joore, Jos, Kustermann, Stefan, Roth, Adrian, Hankemeier, Thomas, Moisan, Annie, Vulto, Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557798/
https://ncbi.nlm.nih.gov/pubmed/28811479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00259-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars