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High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug candidates. Here we demonstrate a method for culturing three-dimensional networks of spontaneously active neurons and supporting glial cells i...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wevers, Nienke R., van Vught, Remko, Wilschut, Karlijn J., Nicolas, Arnaud, Chiang, Chiwan, Lanz, Henriette L., Trietsch, Sebastiaan J., Joore, Jos, Vulto, Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146966/
https://ncbi.nlm.nih.gov/pubmed/27934939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38856
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