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High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug candidates. Here we demonstrate a method for culturing three-dimensional networks of spontaneously active neurons and supporting glial cells i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wevers, Nienke R., van Vught, Remko, Wilschut, Karlijn J., Nicolas, Arnaud, Chiang, Chiwan, Lanz, Henriette L., Trietsch, Sebastiaan J., Joore, Jos, Vulto, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146966/
https://ncbi.nlm.nih.gov/pubmed/27934939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38856
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