Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans

To elucidate the role of innate responses in vaccine immunogenicity, we compared early responses to hepatitis B virus (HBV) surface antigen (HBsAg) combined with different Adjuvant Systems (AS) in healthy HBV-naïve adults, and included these parameters in multi-parametric models of adaptive response...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Burny, Wivine, Callegaro, Andrea, Bechtold, Viviane, Clement, Frédéric, Delhaye, Sophie, Fissette, Laurence, Janssens, Michel, Leroux-Roels, Geert, Marchant, Arnaud, van den Berg, Robert A., Garçon, Nathalie, van der Most, Robbert, Didierlaurent, Arnaud M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557780/
https://ncbi.nlm.nih.gov/pubmed/28855902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00943
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