Long-Term Persistence of Cell-Mediated and Humoral Responses to A(H1N1)pdm09 Influenza Virus Vaccines and the Role of the AS03 Adjuvant System in Adults during Two Randomized Controlled Trials

We investigated the role of AS03(A) (here AS03), an α-tocopherol oil-in-water emulsion-based adjuvant system, on the long-term persistence of humoral and cell-mediated immune responses to A(H1N1)pdm09 influenza vaccines. In two studies, a total of 261 healthy adults (≤60 years old) were randomized t...

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Publicat a:Clin Vaccine Immunol
Autors principals: van der Most, Robbert G., Clément, Frédéric, Willekens, Julie, Dewé, Walthère, Walravens, Karl, Vaughn, David W., Leroux-Roels, Geert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Clinical Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461372/
https://ncbi.nlm.nih.gov/pubmed/28446441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00553-16
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