Long-Term Persistence of Cell-Mediated and Humoral Responses to A(H1N1)pdm09 Influenza Virus Vaccines and the Role of the AS03 Adjuvant System in Adults during Two Randomized Controlled Trials

We investigated the role of AS03(A) (here AS03), an α-tocopherol oil-in-water emulsion-based adjuvant system, on the long-term persistence of humoral and cell-mediated immune responses to A(H1N1)pdm09 influenza vaccines. In two studies, a total of 261 healthy adults (≤60 years old) were randomized t...

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Publicado en:Clin Vaccine Immunol
Autores principales: van der Most, Robbert G., Clément, Frédéric, Willekens, Julie, Dewé, Walthère, Walravens, Karl, Vaughn, David W., Leroux-Roels, Geert
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Clinical Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461372/
https://ncbi.nlm.nih.gov/pubmed/28446441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00553-16
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