Long-Term Persistence of Cell-Mediated and Humoral Responses to A(H1N1)pdm09 Influenza Virus Vaccines and the Role of the AS03 Adjuvant System in Adults during Two Randomized Controlled Trials

We investigated the role of AS03(A) (here AS03), an α-tocopherol oil-in-water emulsion-based adjuvant system, on the long-term persistence of humoral and cell-mediated immune responses to A(H1N1)pdm09 influenza vaccines. In two studies, a total of 261 healthy adults (≤60 years old) were randomized t...

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Bibliografische gegevens
Gepubliceerd in:Clin Vaccine Immunol
Hoofdauteurs: van der Most, Robbert G., Clément, Frédéric, Willekens, Julie, Dewé, Walthère, Walravens, Karl, Vaughn, David W., Leroux-Roels, Geert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Clinical Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461372/
https://ncbi.nlm.nih.gov/pubmed/28446441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00553-16
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