H5N1 Influenza Vaccine Formulated with AS03(A) Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses

OBJECTIVE: Adjuvantation of an H5N1 split-virion influenza vaccine with AS03(A) substantially reduces the antigen dose required to produce a putatively protective humoral response and promotes cross-clade neutralizing responses. We determined the effect of adjuvantation on antibody persistence and B...

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Main Authors: Moris, Philippe, van der Most, Robbert, Leroux-Roels, Isabel, Clement, Frédéric, Dramé, Mamadou, Hanon, Emmanuel, Leroux-Roels, Geert G., Van Mechelen, Marcelle
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132412/
https://ncbi.nlm.nih.gov/pubmed/21174144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9490-6
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